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We report four children with idiopathic stroke syndromes who were assayed for human leukocyte antigen(HLA)class I markers and found to have HLA-B51 in common.This fining suggests that there may be a genetic predisposition for"idiopathic"childhood stroke,and host factors or viruses,may play a major role in the mechanism of unexplained occlusion of the cerebral vasculature in children. |
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